WATER-ABSORBING BIPHASE BIOADHESIVE COMPOSITIONS Russian patent published in 2006 - IPC A61L15/58 A61F13/02 

FIELD: medicine.

SUBSTANCE: invention describes a bioadhesive composition useful for medicinal agents applied on skin or other patient body surfaces and comprising hydrophobic phase and hydrophilic phase. Hydrophobic phase comprises cross-linked butyl rubber or butyl rubber cross-linked with polyisobutylene and hydrophilic phase comprises a mixture of hydrophilic polymer and complementary oligomer able for cross-linking of hydrophilic polymer. Hydrophilic polymer is chosen from the group comprising poly-(N-vinyllactames), poly-(N-vinylamides), poly-(N-alkylacrylamides), polyacrylic acid, polymethacrylic acid, polyvinyl alcohol, polyvinylamide, their copolymers and mixtures. Complementary oligomer is chosen from the group comprising polyhydric alcohols, monomeric and oligomeric alkylene glycols, polyalkylene glycols, polyalkylene glycols with terminal carboxyl-groups, polyalkylene glycols with terminal amino-groups, incomplete polyhydric alcohol esters, alkanediols and carboxylic diacids. Adhesive has no irritating, comedogenous and sensitizing properties, it sticks to skin at insignificant pressure.

EFFECT: valuable medicinal properties of compositions.

27 cl, 2 tbl, 10 dwg, 4 ex