FIELD: medicine.
SUBSTANCE: the present innovation deals with diagnostics in vitro hypertension diathesis caused with genetic factors due to detecting in a sample (a) SNP which should be detected in exon 8(C→T) of hsgk1 gene and presented in SEQ ID NO:1, and also (B) SNP which should be detected in intron 6(T→C) of hsgk1 gene and localized in a fragment of 551 size being opposite the transcription against SNP in exon 8 according to item (a), or both SNP according to items (a) and (b). The innovation refers, also, to application of such SNP for obtaining a diagnostic kits and sets for carrying out diagnostics of hypertension diathesis caused with genetic factors. The method provides concrete sequences of hsgk1 gene that cause hypertension diathesis.
EFFECT: higher accuracy and efficiency of diagnostic analysis.
3 cl, 2 ex, 5 tbl
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