METHOD FOR PREDICTION OF BLOOD PRESSURE LEVEL IN PREGNANT WOMEN DEPENDING ON GENETIC ENDOTHELIN 1 POLYMORPHISM Russian patent published in 2013 - IPC G01N33/53 

Abstract RU 2473912 C1

FIELD: medicine.

SUBSTANCE: method for prediction of blood pressure level in pregnant women involves DNA recovery from peripheral venous blood lymphocytes and analysis of endothelin 1 (ET-1) K198N gene polymorphism by polymerase chain reaction. Observing the 198K allele of K198N ET-1 polymorphism enables predicting a risk of blood pressure increase in pregnant women on their 37-40 weeks of pregnancy.

EFFECT: invention provides producing an effective assessment criterion of blood pressure variation in pregnant women enable a pre-pregnancy possibility of upward blood pressure variation and applying a specific approach to pregnant woman management over the whole period of gestation.

1 dwg, 3 tbl, 1 ex

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RU 2 473 912 C1

Authors

Churnosov Mikhail Ivanovich

Reshetnikov Evgenij Aleksandrovich

Akulova Ljudmila Jur'Evna

Kolesnikov Jurij Vasil'Evich

Polonikov Aleksej Valer'Evich

Dates

2013-01-27Published

2011-09-30Filed