FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, in particular to a method for testing a dog for predisposition of a dog to accumulation of copper in a liver, involving detection in a sample of the presence or absence of one or more polymorphisms in a dog's genome, selected from: (a) Chr22_3167534 (SEQ ID NO: 144), Chr22_3135144 (SEQ ID NO: 145), Chr20_55461150 (SEQ ID NO: 146), ChrX_120879711 (SEQ ID NO: 147), Chr19_6078084 (SEQ ID NO: 148), Chr15_62625262 (SEQ ID NO: 149), Chr14_39437543 (SEQ ID NO: 150), Chr15_62625024 (SEQ ID NO: 151), Chr3_86838677 (SEQ ID NO: 152), Chr24_4011833 (SEQ ID NO: 153), Chr18_60812198 (SEQ ID NO: 154), Chr10_65209946 (SEQ ID NO: 155) and repeating CGCCCC in chromosomal position 22:3135287; (b) one or more polymorphisms in a nonequilibrium cohesion with said polymorphism (a), and/or (c) Chr32_38904515 (SEQ ID NO: 156), Chr8_4892743 (SEQ ID NO: 157) and Chr8_4880518 (SEQ ID NO: 158).
EFFECT: disclosed is a genetic test for copper accumulation in liver in dogs.
9 cl, 10 dwg, 21 tbl, 6 ex
