FIELD: pharmaceutics.
SUBSTANCE: the present innovation deals with mixing dry St. John's wort extract with additional substances followed by compressing, sieving, treating compact extract with additional substances including titanium dioxide and talc with subsequent tableting, moreover, compressing should be carried out with highly dispersed silicon dioxide only, at a certain portion of silicon dioxide supplemented before compression, one should apply the particles of compact extract at certain distribution according to the size of particles to achieve certain bulk density of particles of compact extract and density after compression; the particles of compact extract should be additionally covered with combination of aerators chosen out of sodium-crosscarmelose, sodium-carboxymethyl starch. The above-mentioned method enables to obtain tablets at high portion of extract, high characteristics of decomposition and releasing of biologically active substances.
EFFECT: higher efficiency.
5 cl
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Authors
Dates
2006-11-20—Published
2002-07-15—Filed