IBUPROFEN-CONTAINING COMPOSITION Russian patent published in 2007 - IPC A61K9/20 A61K9/28 A61K31/19 A61P29/00

Abstract RU 2300368 C2

FIELD: medicine, pharmacy.

SUBSTANCE: invention describes a method for preparing a composition containing ibuprofen that represents active substance possessing anti-inflammatory, analgesic and antipyretic effects. Method involves covering ibuprofen or its salts with hydroxymethylpropylcellulose, methylcellulose, carboxymethylcellulose sodium, hydroxypropylcellulose or gelatin as a binding agent wherein part of binding agent is from 0.1 to 10 wt.-%, and part of ibuprofen or its salts is from 90 to 99.9 wt.-% as measured for dry weight. The composition can be pressed directly to form solid medicinal formulations showing hardness and stability against abrasion, stability in storage and wherein active substance is released in desired time, Medicinal preparation can be used directly for making tablets of different size and with different dose of ibuprofen.

EFFECT: improved preparing method, improved pharmaceutical properties of composition and tablets.

10 cl, 5 tbl, 3 ex

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RU 2 300 368 C2

Authors

Ajnikh Khajnts

Dates

2007-06-10—Published

2001-01-19—Filed