FIELD: medicine, infectious diseases, vaccines.
SUBSTANCE: invention relates to development and using mixed vaccines used in prophylaxis and treatment of infections being at first hepatitis B. The mixed vaccine comprises hepatitis B virus surface antigen adsorbed on aluminum phosphate and mixed with antigens of another pathogens adsorbed on aluminum hydroxide or aluminum phosphate taken in the amount n = 3-4 and chosen from diphtheria, tetanus, whooping cough and Haemophilus influenza b. At least one antigen among antigens n and other pathogens is adsorbed on aluminum hydroxide. Aluminum phosphate confers the resistance to hepatitis B surface antigen in polyvalent compositions of vaccines. Polyvalent vaccines are stable and show higher immunological indices in their administration in children.
EFFECT: improved preparing method, valuable medicinal properties of vaccines.
5 cl, 16 tbl, 11 ex
| Title |
Year |
Author |
Number |
| COMBINED VACCINE BASED ON SURFACE HEPATITIS B VIRUS ANTIGEN, METHOD OF PREPARATION THEREOF, AND METHOD FOR PREVENTING HEPATITIS B INFECTION IN MAN |
1993 |
|
RU2160120C2 |
| COMBINED VACCINE TO PREVENT WHOOPING COUGH, DIPHTHERIA, TETANUS, HEPATITIS AND INFECTIONS CAUSED BY TYPE B HAEMOPHILUS INFLUENZAE |
2015 |
- Nikolaeva Alevtina Maksimovna
- Semenova Valentina Danilovna
- Speranskaya Vera Nikolaevna
- Sosnina Oksana Yurevna
- Gryaznova Diana Vasilevna
- Pushkareva Elena Valentinovna
|
RU2626532C2 |
| MIXED VACCINE FOR IMMUNOPROPHYLAXIS OF WHOOPING COUGH, DIPHTHERIA, TETANUS AND VIRAL HEPATITIS B AND D |
2003 |
- Borisova V.N.
- Budanov M.V.
- Jakovleva I.M.
- Mel'Nikov V.A.
|
RU2233673C1 |
| COMBINED VACCINES WITH LOW-DOSE Hib CONJUGATE |
2005 |
|
RU2435609C2 |
| COMBINED HEPTAVALENT VACCINE |
2012 |
- Kuppuswamy, Gopinathan
- Thiagarajan, Vijayanand
|
RU2705163C2 |
| MIXED VACCINE FOR IMMUNE PROPHYLAXIS OF VIRAL HEPATITIS B, TETANUS, DIPHTHERIA AND WHOOPING COUGH |
1998 |
- Borisova V.N.
- Mel'Nikov V.A.
- Budanov M.V.
- Jakovleva I.M.
- Petrov V.F.
- Efimova N.P.
- Nikolaeva A.M.
- Pushkareva E.V.
- Grjaznova D.V.
|
RU2130778C1 |
| MIXED VACCINE FOR IMMUNE PROPHYLAXIS OF VIRAL HEPATITIS B, TETANUS AND DIPHTHERIA |
1998 |
- Borisova V.N.
- Mel'Nikov V.A.
- Budanov M.V.
- Jakovleva I.M.
- Petrov V.F.
- Efimova N.P.
- Nikolaeva A.M.
- Pushkareva E.V.
- Grjaznova D.V.
|
RU2130779C1 |
| COMBINED VACCINE CONTAINING DIPHTHERIA, TETANUS, ACELLULAR PERTUSSIS, HAEMOPHILUS INFLUENZAE AND POLIOVIRUS ANTIGENS, USING IT AND METHOD FOR PREPARING IT |
2009 |
- Dzhain Radzhesh
- Singkh Sukkhdzhit
- Zhdambu Lavit
|
RU2526214C2 |
| COMBINED VACCINE WITH ACELLULAR PERTUSSIS |
2013 |
- Jain Rajesh
- Singh Sukhjeet
- Jambu Lavit
|
RU2634393C2 |
| MIXED VACCINE FOR IMMUNOPROPHYLAXIS OF VIRAL HEPATITIS B AND D, TETANUS AND DIPHTHERIA |
2003 |
- Borisova V.N.
- Budanov M.V.
- Jakovleva I.M.
- Mel'Nikov V.A.
|
RU2233672C1 |
