FIELD: medicine.
SUBSTANCE: presented combined vaccine contains the following components: whooping cough component, which is 60-70 μg of purified acellular whooping cough vaccine, diphtheria toxoid - 15-20 Lf, tetanus toxoid 5-7.5 Lf, 5-10 μg of recombinant hepatitis B surface antigen (HBsAg), 8-12 μg of type b conjugated Haemophilus influenzae (Hib) vaccine, 0.3 to 0.55 mg of aluminium hydroxide (in terms of aluminium Al3+). The described vaccine is an enhanced non-toxic drug, enabling simultaneous immunization against whooping cough, diphtheria, tetanus, hepatitis and infections caused by type b Haemophilus influenzae.
EFFECT: use of the invention allows to expand the arsenal of tools for vaccination of children in accordance with the national calendar of preventive vaccination of Russia.
4 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMBINED HEPTAVALENT VACCINE | 2012 |
|
RU2705163C2 |
| COMBINED VACCINE FOR PREVENTING PERTUSSIS, DIPHTHERIA, TETANUS | 2015 |
|
RU2596919C2 |
| MIXED VACCINE FOR IMMUNE PROPHYLAXIS OF VIRAL HEPATITIS B, TETANUS, DIPHTHERIA AND WHOOPING COUGH | 1998 |
|
RU2130778C1 |
| MULTIPLE VACCINATION INCLUDING SEROGROUP C MENINGOCOCCI | 2006 |
|
RU2457858C2 |
| THE MIXED VACCINE, A METHOD OF SIMULTANEOUS MIXED VACCINATION AND A METHOD OF IMMUNOGENICITY INCREASE | 1993 |
|
RU2121365C1 |
| COMBINED VACCINES WITH WHOLE CELL PERTUSSIS ANTIGEN | 2006 |
|
RU2420315C2 |
| MULTIPLE VACCINATION INCLUDING SEROGROUP C MENINGOCOCCI | 2012 |
|
RU2641969C2 |
| COMBINED VACCINE CONTAINING DIPHTHERIA, TETANUS, ACELLULAR PERTUSSIS, HAEMOPHILUS INFLUENZAE AND POLIOVIRUS ANTIGENS, USING IT AND METHOD FOR PREPARING IT | 2009 |
|
RU2526214C2 |
| COMBINED VACCINE WITH ACELLULAR PERTUSSIS | 2013 |
|
RU2634393C2 |
| POLYVALENT ASSOCIATED DIPHTHERIA, TETANUS TOXOIDS AND PERTUSSIS POLIOVIRUS VACCINES | 1997 |
|
RU2194531C2 |
