METHOD FOR PREDICTING MORPHOLOGICAL ALTERATIONS IN LARGE ARTERIES Russian patent published in 2006 - IPC A61B5/295 

FIELD: medicine, forensic medicine.

SUBSTANCE: the present innovation deals with predicting morphological alterations in the walls of large arteries. One should detect a stiffness index (SI) according to characteristics of neutralized volumetric pulse curve registered upon a finger due to photoplethysmographic technique. Moreover, pulse wave should be registered after sublingual intake of 500 mcg nitroglycerin. As a value for elastic component of arterial stiffness one should taken into account a minimal SI value (SI_min) BP of 4 neutralized volumetric pulse curves that corresponds to maximal arterial dilation. Then it is necessary to calculate the thickness of intima-media complex (TIM) in middle segments of general carotid arteries by the following formula: TIM=0.0484xSI_min+0.3135, where TIM - thickness of intima-media complex (mm); SI_min - minimal SI value out of 4 volumetric pulse curves obtained after intake of nitroglycerin (m/sec). The innovation enables to elaborate quantitative criteria for detecting morphological alteration in large arteries due to photoplethysmography.

EFFECT: higher accuracy of diagnostics.

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