METHOD FOR DETERMINATION OF MARKERS OF EARLY AND LATE REMODELING OF SUPRARENAL AND INFRARENAL DEPARTMENTS OF AORTA IN PATIENTS WITH DIFFERENT DEGREE OF ARTERIAL HYPERTENSION USING ULTRASOUND METHODS Russian patent published in 2017 - IPC A61B8/00 

FIELD: medicine.

SUBSTANCE: two methods are used simultaneously: duplex angioscanning and pulsed-wave tissue dopplerography. By means of duplex angioscanning, changes in the structural and functional properties of the abdominal aorta are revealed: a decrease in systolic-diastolic aortic augmentation ΔD, a decrease in the compliance coefficient CC and the ductility coefficient CD and an increase in the stiffness index SI, Peterson's elasticity modulus Ep and Young's modulus Einc of the aorta, an increase in the circumferential stress CWS on the walls of the aorta. Using the pulse-wave tissue dopplerography method, markers of early aortic remodeling that characterize changes in the phase structure of the spectrum of the anterior and posterior walls of the suprarenal and infrarenal divisions of the aorta are determined: appearance of a two-phase curve of aortic walls movement as a result of the absence of E and S2 peaks, a decrease in the peak velocities VS1max, VDmax and an increase in the duration of aortic walls movement to the diastole TVDmax. The markers of late remodeling of the suprarenal and infrarenal aortic sections are determined: an increase in the diastolic diameter Dd of the suprarenal aorta and the thickness of the intima-media complex TIMC of the suprarenal and infrarenal aortic sections walls, an increase in the duration of aortic walls movement to the systole TVS1max.

EFFECT: method allows to conduct a complex ultrasound evaluation of the structural and functional state of the suprarenal and infrarenal aortic divisions in patients with different degrees of arterial hypertension in a non-invasive manner, which provides an opportunity for treatment correction and primary prevention of vascular complications in patients with arterial hypertension.

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