PHARMACEUTICAL COMPOSITION THAT INHIBIT VASCULAR PROLIFERATION AND METHOD FOR THEIR USING Russian patent published in 2006 - IPC A61K38/31 A61K31/404 A61P43/00

Abstract RU 2288739 C2

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to a method for treatment of vascular proliferation in a patient. Method involves administration of agonist of somatostatin receptor type 1 in the therapeutically effective dose to a patient wherein indicated agonist of somatostatin receptor type 1 show the inhibition constant value (K_i) lower 5 nM for somatostatin receptor type 1 and its K_i value for somatostatin receptor type 1 at least by 10 times lower as compared with K_i values for each somatostatin receptors type 2, type 3, type 4 and type 5. Invention provides the maximal inhibition of unfavorable vascular proliferation at minimal symptoms of adverse effects based on the selective anti-angiogenic effect of agonist of somatostatin receptor type 1.

EFFECT: valuable medicinal properties of compositions.

12 cl, 3 tbl, 16 dwg

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RU 2 288 739 C2

Authors

Devitt Kaller Majkl

Danezi Romano

Bochchi Gvido

Del'Takka Mario

Dates

2006-12-10—Published

2002-01-14—Filed