FIELD: medicine, pharmacy, pharmacology.
SUBSTANCE: invention relates to a pharmaceutical composition comprising the medicinal preparation afobasol as an active component. Indicated pharmaceutical composition is prepared as a tablet formulation and comprises medicinal preparation afobasol, i. e. 5-ethoxy-2-[2-(morpholino)ethylthio]benzimidazole hydrochloride, eliciting the expressed anxiolytic activity in the broad range of doses. The composition comprises small amounts of special additives, such as lactose, starch, polyvinylpyrrolidone, stearic acid or stearate. Invention provides easy release of active component that provides its high bioavailability. Tablets satisfy all requirements of the State Pharmacopoeia of XI edition.
EFFECT: improved and valuable pharmaceutical and medicinal properties of pharmaceutical composition.
8 cl, 1 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| "NOOPEPT"-BASE PHARMACEUTICAL COMPOSITION | 2004 |
|
RU2289422C2 |
| SOLID INDIVIDUAL HIGH 2-ETHYL-6-METHYL-3-PYRIDIN-3-OLE HYDROCHLORIDE DOSAGE FORM AND METHOD FOR PREPARING IT | 2010 |
|
RU2448686C1 |
| ANTIVIRAL AGENT AND METHOD OF PREPARATION THEREOF | 2000 |
|
RU2160105C1 |
| PHARMACEUTICAL COMPOSITION IN FORM OF TABLET AND METHOD OF OBTAINING THEREOF | 2014 |
|
RU2546002C1 |
| IRBESARTAN-CONTAINING PHARMACEUTICAL COMPOSITIONS | 1996 |
|
RU2181590C2 |
| IRBESARTAN-CONTAINING PHARMACEUTICAL COMPOSITIONS | 1996 |
|
RU2210368C1 |
| PHARMACEUTICAL COMPOSITION WITH ANTIHYPERTENSIVE ACTIVITY AND METHOD OF PREPARATION THEREOF | 2000 |
|
RU2169005C1 |
| PHARMACEUTICAL COMPOSITION SHOWING ANTIULCER ACTIVITY AND METHOD OF ITS PREPARING | 2000 |
|
RU2155035C1 |
| COMPOSITION OF BIS-PHOSPHONIC ACIDS FOR WET GRANULATION | 1995 |
|
RU2149003C1 |
| PHARMACEUTICAL COMPOSITION EXHIBITING ANTIVIRAL EFFECT | 1999 |
|
RU2145218C1 |
