FIELD: biotechnology.
SUBSTANCE: 4-[4-[4-(hydroxybiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylphenylacetic acid is produced by incubation of mixture, containing terphenadine and microorganism capable to produce said acid followed by isolation of target product.
EFFECT: simplified process with increased yield.
20 cl, 2 tbl
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NEW CRYSTALLINE FORMS OF 4-[4-[4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL]-1-HYDOXYBUTHYL-α, α-DYMETHYLBENZENEACETIC ACID AND HYDROCHLORIDE THEREOF AND METHOD FOR PRODUCTION THE SAME | 2001 |
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Authors
Dates
2006-12-27—Published
2001-11-06—Filed