FIELD: medicine, pharmacology, pharmacy.
SUBSTANCE: invention relates to a method for enhancing availability of epotilone analog. Method involves oral administration of epotilone analog or its pharmaceutically acceptable salt, solvate, clathrate, hydrate or a prodrug in mammal in combination with pharmaceutically acceptable buffer neutralizing acid in the amount providing at least 20 mequiv. of capacity for acid neutralization that results to improving bioavailability of epotilone.
EFFECT: improved properties of formulations of drug.
20 cl, 5 tbl, 2 dwg, 9 ex
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