FIELD: medicine.
SUBSTANCE: method involves preparing composition comprising epotilone analogs by dissolving said epotilone analog in aqueous butanol. The produced solution is dried in two stages to produce lyophilized product being lyophilized epotilone analog and pharmacological means for treating cancer diseases containing lyophilized epotilone analog.
EFFECT: high solubility of obtained product.
20 cl,1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| EPOTILONE PHARMACEUTICAL DOSED FORMULATION FOR ORAL ADMINISTRATION | 2002 |
|
RU2291695C2 |
| EPOTHILONE-CONTAINING COMPOSITIONS | 1999 |
|
RU2214246C2 |
| THERAPEUTIC COMPOSITIONS | 2004 |
|
RU2358729C2 |
| LYOPHILIZED COMPOSITION | 1999 |
|
RU2268045C2 |
| POLYMORPHIC MODIFICATIONS OF EPOTILONE ANALOG, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF | 2001 |
|
RU2272039C2 |
| COMPOSITIONS CONTAINING SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 | 2002 |
|
RU2333754C2 |
| EPOTHILONE DERIVATIVE FOR TREATMENT OF HEPATOME AND OTHER CANCER DISEASES | 2003 |
|
RU2358730C2 |
| COMBINATIONS CONTAINING TRANSDUCTION SIGNAL INHIBITOR AND EPOTILONE DERIVATIVE | 2002 |
|
RU2313345C2 |
| COMBINATIONS CONTAINING ANTIDIARRHEAL AGENT AND EPOTHYLON OR EPOTHYLON DERIVATIVES | 2002 |
|
RU2330661C2 |
| COMBINATIONS CONTAINING EPOTHILONES AND ANTIMETABOLITES | 2003 |
|
RU2346686C2 |
