USE OF FLAVONOLIGNANS FOR INHIBITION OF EXCESSIVE AND PATHOLOGICAL PROLIFERATION OF VESSEL ENDOTHELIUM Russian patent published in 2007 - IPC A61K36/28 A61P35/00 

Abstract RU 2291706 C1

FIELD: medicine, pharmacology.

SUBSTANCE: agent represents flavolignans chosen from silybinine, silydianine, silycrystine, dehydrosilybinine, their mixtures or extracts prepared from plant spotted milk thistle (Silybium marianum (L.) Gaertn) containing these components. Agent is used for inhibition of excessive or pathological proliferation of vascular endothelium. Proposed agent expands assortment of agents directed for treatment pathologies associated with angiogenesis disorders. Invention can be used in development of medicinal preparations used in therapy of pathologies associated with angiogenesis disorders, namely, for inhibition of excessive or pathological proliferation of vascular endothelium.

EFFECT: valuable medicinal properties of agent.

1 tbl, 2 dwg, 2 ex

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RU 2 291 706 C1

Authors

Digtjar' Anton Vasil'Evich

Lutsenko Elena Valer'Evna

Lutsenko Sergej Viktorovich

Fel'Dman Natal'Ja Borisovna

Dates

2007-01-20Published

2005-06-21Filed