FIELD: medicine.
SUBSTANCE: invention concerns pharmacology and medicine, namely to preparations based on Saint-Mary-thistle extracts, and can be used for therapy of hepatic pathologies and malignant neoplasms. The composition represents a noncovalent complex wherein as an excipient, human or mammal blood plasma protein is used with the flavolignane to protein ratio (1-150): 1. In the composition as human or mammal blood plasma protein, albumin, prealbumin, alpha-fetoprotein, alpha- or beta-globulin or their peptide fragments are used. Besides as alpha globulin, the composition contains lipoproteins, transcortin, acidic glycoprotein, thyroxine-binding globulin, haptoglobin, plasminogen, macroglobulin, retinol-binding protein, vitamin D-binding protein, while beta globulin is as follows - lipoproteins, transferrin, globulin binding connecting sex hormones, transcobalamin.
EFFECT: ensured double therapeutic action: realisation of hepatoprotective or antineoplastic activity combined with the plasma-substituting therapy in hypoproteinemia accompanying an underlying disease.
4 cl, 3 tbl, 2 ex
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Authors
Dates
2010-01-20—Published
2008-11-18—Filed