FIELD: immunology, biotechnology.
SUBSTANCE: described are rabies virus-neutralizing antibody and fragments thereof; method for treatment of subject being affected by rabies virus using said antibody and fragments thereof. Disclosed are variants of isolated nucleic acids, encoding polypeptides bearing light and/or heavy antibody strain, respectively. Disclosed is expression vector bearing at least one from abovementioned nucleic acids. The invention makes it possible to increase subject survival after rabies virus attack.
EFFECT: method for prophylaxis and treatment of rabies virus infections.
14 cl, 1 tbl, 5 ex
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RABIES VIRUS-SPECIFIC HUMAN NEUTRALIZING MONOCLONAL ANTIBODY AND NUCLEIC ACID AND METHODS ASSOCIATED WITH THEREOF | 2001 |
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Authors
Dates
2007-01-27—Published
2002-08-21—Filed