FIELD: biotechnology; immunology; medicine.
SUBSTANCE: disclosed are a recombinant fusion protein based on a single-domain antibody, specifically binding and neutralizing rabies virus, a Chinese hamster ovary cell line strain, producing said protein, a method of producing said protein and using said protein as an agent for passive immunization against rabies.
EFFECT: invention enables to obtain a recombinant fusion protein with a prolonged half-life, which can be used for passive immunization in the scheme of emergency therapeutic immunization against rabies, without reducing the efficacy of the anti-rabies vaccine.
7 cl, 8 dwg, 3 tbl, 7 ex
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