METHOD FOR DETERMINING LIDOCAINE HYDROCHLORIDE QUANTITY Russian patent published in 2007 - IPC G01N33/15 

Abstract RU 2293985 C2

FIELD: analytical chemistry; medicine.

SUBSTANCE: method involves applying copper (II) salicylate complex with following obtained colored compound extraction and photometric examination of the extract. Copper (II) sulfate and sodium salicylate solutions taken in volume proportion of 0.8-1.8-1.0-2.2 ml per volume of sample under analysis are added to the preparation solution amount equal to 1 ml of 1% lidocaine hydrochloride solution. After having treated the mixture with the reagent, extraction with chloroform is carried out and optical density of the extract is measured at wavelength λ=750 nm. Lidocaine hydrochloride amount is determined from calibration plot.

EFFECT: improved specificity, selectivity of the method.

1 dwg, 7 tbl

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RU 2 293 985 C2

Authors

Nokhrin Dmitrij Fokeevich

Kolmakova Ljudmila Sergeevna

Saraeva Ol'Ga Artemovna

Nikolajchik Oksana Petrovna

Dates

2007-02-20Published

2004-11-09Filed