METHOD FOR TREATING INTRAOCULAR DISEASES Russian patent published in 2007 - IPC A61F9/08 A61K31/409 A61P35/00 

Abstract RU 2295944 C1

FIELD: medicine, ophthalmology, ophthalmooncology.

SUBSTANCE: one should intravenously inject a photosensitizer photosens at 0.1-1.0 mg/kg patient's body weight. In about 48-72 h since the moment of photosens injection it is important to detect the presence of preparation's therapeutic dosage in the tumor. For this purpose one should specify the coefficient of contrast degree between the tumor and healthy adjacent tissues. Planning of photodynamic therapy should be fulfilled individually by orienting to concrete values of the coefficient of contrast degree in a concrete patient. At the value of coefficient of contrast degree being ≥4, but under 10 it is necessary to irradiate with low single dosages (ranged 80-150 mW/sq. cm) by increasing the number of seances conducted (up to 10). At the value of the above-mentioned coefficient being ≥10.0 irradiation should be carried out once or during 2-3 seances at high single radiation dosages (ranged 150-800 mW/sq. cm). The innovation enables to optimize therapy in patients with intraocular tumors.

EFFECT: higher efficiency of therapy.

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Authors

Likhvantseva Vera Gennad'Evna

Budzinskaja Marija Viktorovna

Merzljakova Oksana Jur'Evna

Shevchik Sergej Aleksandrovich

Loshchenov Viktor Borisovich

Vorozhtsov Georgij Nikolaevich

Kuz'Min Sergej Georgievich

Dates

2007-03-27Published

2005-07-12Filed