FIELD: medicine.
SUBSTANCE: method involves performing orbitotomy for excising tumor ad maximum and applying inraoperative photodynamic therapy and chemotherapy. Photosensitizing agent is introduced at a dose of 0.1-1.0 mg/kg of body weight 3 days before the operation. The postoperative cavity formed as a result of operation is filled with physiologic saline immediately after removing the tumor and washing-off the operation wound. Cylindrical diffuser light guide is introduced into the wound and laser radiation treatment is carried out at 670 nm wavelength and power density of 120-800 mW/cm2. The physiologic saline is removed. The light guide is withdrawn. The wound is sutured. Chemotherapy is applied in postoperative period.
EFFECT: enhanced effectiveness of tumor destruction; reduced risk of post-irradiation complications.
5 dwg
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Authors
Dates
2006-10-27—Published
2005-04-13—Filed