FIELD: chemistry of heterocyclic compounds, medicine, pharmacy.
SUBSTANCE: invention relates to novel compounds of the formula (1): and their salts wherein values R1, k, Ar, n, j, Y, R and R2 are determined in the invention claim. Novel compounds are able to modulate activity of chemokine receptors. Also, invention relates to using indicated compounds for treatment of human immunodeficiency virus or feline immunodeficiency virus and to a pharmaceutical composition based on thereof.
EFFECT: valuable medicinal properties of compounds and pharmaceutical composition.
16 cl, 100 ex
Title | Year | Author | Number |
---|---|---|---|
HETEROCYCLIC COMPOUNDS, THEIR USING AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF STATES MEDIATED BY CXCR4 AND CCR5 | 2001 |
|
RU2277092C2 |
HETEROCYCLIC COMPUNDS WITH HIGHER EFFICIENCY COUPLING WITH CHEMOKINE RECEPTOR | 2002 |
|
RU2325387C2 |
HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND THEIR USING | 2001 |
|
RU2289581C2 |
METHODS FOR PRODUCTION OF RACEMIC AMINOSUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE OR RACEMIC AMINOSUBSTITUTED 5,6,7,8-TETRAHYDROISOQUINOLINE, METHODS FOR SEPARATION AND RACEMIZATION THEREOF, METHODS FOR PRODUCTION OF KETOSUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE OR KETOSUBSTITUTED 5,6,7,8-TETRAHYDROISOQUINOLINE, METHOD FOR PRODUCTION OF ENANTIOMER PF CONDENSED BYCYCLIC RING SUBSTITUTED WITH PRIMARY AMINE, 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES | 2002 |
|
RU2308451C2 |
ARYLMETHOXY ISOINDOLIN DERIVATIVE, COMPOSITIONS INCLUDING THEREOF AND METHODS OF THEIR APPLICATION | 2011 |
|
RU2567753C2 |
SUBSTITUTED PYRIDINE COMPOUND | 2011 |
|
RU2572606C2 |
USING EP4 RECEPTOR LIGANDS IN TREATMENT OF IL-6-MEDIATED DISEASES | 2003 |
|
RU2285527C2 |
CONDENSED HETEROCYCLIC COMPOUNDS | 2006 |
|
RU2408586C2 |
HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USE THEREOF | 2016 |
|
RU2743360C2 |
DERIVATIVES OF TETRAHYDROQUINOLINE SHOWING PROTECTIVE ACTION FROM HIV-INFECTION | 2005 |
|
RU2350604C2 |
Authors
Dates
2007-04-20—Published
2001-09-17—Filed