HETEROCYCLIC COMPOUNDS MODULATING ACTIVITY OF CHEMOKINE RECEPTOR, THEIR USING AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF Russian patent published in 2007 - IPC C07D403/12 C07D413/14 C07D403/14 C07D401/14 C07D417/14 C07D405/14 A61K31/47 A61P31/18 

Abstract RU 2297413 C2

FIELD: chemistry of heterocyclic compounds, medicine, pharmacy.

SUBSTANCE: invention relates to novel compounds of the formula (1): and their salts wherein values R1, k, Ar, n, j, Y, R and R2 are determined in the invention claim. Novel compounds are able to modulate activity of chemokine receptors. Also, invention relates to using indicated compounds for treatment of human immunodeficiency virus or feline immunodeficiency virus and to a pharmaceutical composition based on thereof.

EFFECT: valuable medicinal properties of compounds and pharmaceutical composition.

16 cl, 100 ex

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RU 2 297 413 C2

Authors

Bridzher Gari

Skerldzh Renato

Kehller Ehl

Kharvig Kertis

Bogutskij Dehvid

Uilson Trevor R.

Kroford Dzhejson

Makichern Ehrnest Dzh.

Atsma Bem

Nan Sikvajao

Zou Juanksi

Skhols Dominik

Smit Kristofer Dennis

Di Fluri Rozaria Marija

Dates

2007-04-20Published

2001-09-17Filed