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(19)

(11)

2 299 887

(13)

(51)

IPC

C07K11/00(2006-01-01)

C07K11/02(2006-01-01)

A61K38/15(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2003102633/04, 2001-07-02

(24)

Start date

2001-07-02

(22)

Actual filing date

2001-07-02

(45)

Published

2007-05-27

(72)

Inventor

Rodriges IgnasioPolanko Konseps'OnKuehvas FeliksMendes PalomaKuehvas KarmenGal'Ego PilarMant SajmonMansanares Ignasio

(73)

Holder

Farma Mar, S.A.

METHODS FOR SYNTHESIS OF APLIDINE AND NOVEL ANTI-TUMOR DERIVATIVES, METHODS FOR THEIR INDUSTRIAL PREPARING AND USING Russian patent published in 2007 - IPC C07K11/00 C07K11/02 A61K38/15 A61P35/00

Abstract RU 2299887 C2

FIELD: organic chemistry, antibiotics, medicine, oncology.

SUBSTANCE: invention relates to novel derivatives of aplidine possessing anti-tumor activity and represented by the general formula:

EFFECT: valuable medicinal property of compound, improved methods of synthesis and preparing.

28 cl, 3 tbl, 121 ex

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RU 2 299 887 C2

Authors

Rodriges Ignasio

Polanko Konseps'On

Kuehvas Feliks

Mendes Paloma

Kuehvas Karmen

Gal'Ego Pilar

Mant Sajmon

Mansanares Ignasio

Dates

2007-05-27—Published

2001-07-02—Filed