SUBSTANCE FOR COMPENSATING OSSEOUS DEFECTS AND METHOD FOR ITS OBTAINING Russian patent published in 2007 - IPC A61K6/33 

Abstract RU 2303436 C1

FIELD: medicine.

SUBSTANCE: the suggested substance for compensating osseous defects contains hydroxyapatite, tricalcium phosphate, collagen and, also, additionally it contains collagen-free proteins of bony tissue; components should be taken at a certain content/100 g dry matter. This substance should be obtained due to affecting bony tissue, drying and sterilizing, moreover, one should fulfill demineralization of bony tissue with hydrochloric acid followed by neutralizing the solution obtained with alkali, then comes alkalization of the suspension obtained with calcium oxide at pH value being 11.0-12.0, washing the residue with water up to neutral reaction, then one should perform lyophilized drying and sterilization to mobilize peptide growth factors. The obtained substance is of considerably marked properties to initiate osteogenesis, for it contains growth factors of bony tissue.

EFFECT: higher efficiency of compensation.

2 cl, 26 dwg

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Authors

Kapustin Roman Filippovich

Desjatnichenko Konstantin Stepanovich

Slesarenko Natal'Ja Anatol'Evna

Torba Aleksandr Ivanovich

Kapustin Filipp Romanovich

Dates

2007-07-27Published

2005-10-31Filed