GLYCOPEPTIDE OF GLYCIRRISINE ACID WITH L-PROLIN HUMORAL IMMUNE RESPONSE STIMULATING Russian patent published in 2007 - IPC C07J53/00 C07J63/00 A61P37/04 

Abstract RU 2303601 C2

FIELD: biochemistry.

SUBSTANCE: describes is new chemical compound, namely glycirrisine acid derivative with L-prolin: 3-O-{2-O-[N-(β-O-glucopyranosyluronoyl)-L-prolin-N-(β-D-glucopyranosyluronoyl)-L-prolin]}-(3β,20β)-11-oxoolean-12-en-30-oic acid, stimulating of humoral immune response. Said compound has low toxicity and increases agglutinins levels (by 3,7 times) and hemolysines level (by 3 times) in mouth blood in contrast with control while administrating of 2 mg/kg.

EFFECT: preparation with increased stimulating activity in relation to agglutinin production.

1 cl, 2 ex

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RU 2 303 601 C2

Authors

Kondratenko Rimma Minibaevna

Baltina Lija Aleksandrovna

Baschenko Natal'Ja Zhanovna

Baltina Lidija Ashrafovna

Ismagilova Asija Fakhretdinovna

Khaliullin Ferkat Adel'Zjanovich

Galin Fanur Zufarovich

Tolstikov Genrikh Aleksandrovich

Dates

2007-07-27Published

2005-02-16Filed