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A1

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IPC

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Application

4640006/04, 1989-01-23

(22)

Actual filing date

1989-01-23

(45)

Published

1994-01-30

(72)

Inventor

Baltina L.A.Sakhautdinova G.M.Davydova V.A.Zarudij F.S.Lazareva D.N.Tolstikov G.A.

GLYCOPEPTIDE OF GLYCYRRHIZIC ACID WITH L-GLUTAMIC ACID DIMETHYL ESTER STIMULATING PRIMARY IMMUNE RESPONSE AND NONSPECIFIC RESISTANCE Russian patent published in 1994 - IPC

Abstract SU 1602019 A1

FIELD: organic chemistry, steroid-like glycosides. SUBSTANCE: synthesis is carried out by treatment of glycyrrhizic acid with N-hydroxysuccinimide in the presence of condensing agent-dicyclohexylcarbodiimide in the medium of tetrahydrofuran. Then prepared tris-oxysuccinimide ester of glycyrrhizic acid is reacted with L-glutamic acid methyl ester hydrochloride. The yield is 77% , LD50= 500 mg/kg. Chemical formula of synthesized compound is given in description of invention. EFFECT: detection of compounds showing activity indicated above. 2 tbl

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SU 1 602 019 A1

Authors

Baltina L.A.

Sakhautdinova G.M.

Davydova V.A.

Zarudij F.S.

Lazareva D.N.

Tolstikov G.A.

Dates

1994-01-30—Published

1989-01-23—Filed

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