METHOD FOR PRODUCTION OF SERUM FOR TREATMENT OF PASTEURELLOSIS IN ANIMALS Russian patent published in 2007 - IPC A61K35/16 

FIELD: biotechnology.

SUBSTANCE: claimed method includes antigen production, producer hyperimmunization with said antigen, determination of immunogenic characteristics of producer blood and producer blood drawing followed by separation and conserving of target product. In producer blood serum antibody titer level to surface soluble Pasteurella antigens in passive hemagglutination reaction is determined. Producer blood drawing to obtain serum for treatment of pasteurellosis in pork is carried out at level of antibody titer to surface soluble P. multocida antigens of serological variants A, B, and D of 1:200-400, 1:400-800, 1:400-800, respectively. Producer blood drawing to obtain serum for treatment of pasteurellosis in cattle is carried out at level of antibody titer to surface soluble P. multocida antigens of serological variants A, B, and D of 1:32-400, 1:256-800, 1:128-800, respectively, and P haemolyca of biotype A-I of 1:128-256.

EFFECT: serum with increased specificity and activity.

2 cl, 5 ex