FIELD: medicine, clinical pharmacology, forensic medicine.
SUBSTANCE: in the course of testing the quality of solutions for injections they should be injected under the skin of a piglet's abdomen at the volume being sufficient to create "lemon peel" effect, then one should fix the time, detect the dynamics of post-injectional inflammation of skin and subcutaneous-fatty fiber and in case of irreversible character and the onset of necrotic alterations it is possible to conclude upon low safety of preparations under testing and the chance for provoking post-injectional necrosis due to their application. The innovation provides the chance to detect medicinal iatrogeny due to widening the information upon the quality of medicinal preparations in the form of either availability or absence of necrotic action.
EFFECT: higher quality of testing.
2 ex
Title | Year | Author | Number |
---|---|---|---|
EXPRESS-EVALUATION TECHNIQUE APPLIED FOR SAFETY DEGREE OF INJECTED MEDICINAL AGENTS | 2006 |
|
RU2325641C1 |
METHOD FOR ESTIMATING LOCAL DRUG TOXICITY | 2008 |
|
RU2396562C1 |
RAPID ASSESSMENT OF POSTINJECTION LOCAL DRUG TOXICITY LEVEL | 2007 |
|
RU2367946C1 |
BLEACHING AGENT | 2014 |
|
RU2589682C1 |
METHOD INCREASING SAFETY OF INJECTIONS | 2007 |
|
RU2340361C1 |
METHOD FOR SKIN DISCOLORATION IN BRUISING AREA | 2015 |
|
RU2582215C1 |
METHOD OF POSTINJECTION NECROSIS PREVENTION | 2006 |
|
RU2326662C1 |
WAY OF EXAMINATION OF MEDICAL PRODUCTS SAFETY | 2008 |
|
RU2362163C1 |
MEANS FOR INTRAVITAL SKIN WHITENING NEAR BLUE EYES | 2017 |
|
RU2639485C1 |
AGENT FOR TOPICAL INJECTION CHEMOANESTHESIA | 2004 |
|
RU2274446C2 |
Authors
Dates
2007-08-20—Published
2005-08-12—Filed