METHOD FOR TREATING HODGKIN'S LYMPHOMA Russian patent published in 2007 - IPC A61K31/4172 A61K38/02 A61K31/573 A61K31/704 A61K31/675 A61K31/475 A61K35/28 A61P29/02 

Abstract RU 2304968 C1

FIELD: medicine, oncology.

SUBSTANCE: it is necessary to fulfill the puncture of posterior section of iliac ala to sample 150 ml medullary suspension into the vial with 50 ml hemoconservant. The vial's content should be supplemented with 40 mg/sq. m doxorubicin, 600 mg/sq. m cyclophosphan and 1.4 mg/sq.m vincristine. The mixture obtained should be incubated at 37°C for 40 min. Then this mixture should be injected for a patient intravenously by drops. Then it is important to conduct infusion of 375 mg/sq.m dacarbazine on the 1st d of therapy. Since the 1st to the 10th d they prescribe per 40 mg/sq. m prednisolone. On the 8th d of therapy one should intravenously inject 10 mg/sq. m bleomycin. The course should be repeated in 14 d. The innovation enables to apply automyelochemotherapy on the 3d-4th stage of systemic malignant disease as the main type of therapy by preventing the increased rate of aseptic necroses of capuit femoris in this category of patients due to the matched injection scheme.

EFFECT: higher efficiency of therapy.

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RU 2 304 968 C1

Authors

Sidorenko Jurij Sergeevich

Kholodnyj Mikhail Davidovich

Tikhanovskaja Natalija Mikhajlovna

Dates

2007-08-27Published

2005-11-22Filed