FIELD: veterinary medicine.
SUBSTANCE: the vaccine suggested contains cell suspension of pure cultures of Pseudomonas aeruginosa agent as antigens that belong to ten sero-groups N18(01); N47(02); N37(03); N19(04); N2(06); N13(010), N70(011); N66(013); N29(018); N28(019) obtained due to selecting parenchymal affected organs from dead animals out of local epizootic focus, inoculating onto differential-diagnostic media and isolating pure cultures of agents. Raising of pure cultures of agents should be carried out separately in meat-peptone broth and agar up to concentration of every sero-group of microbial cells to be about 9.5-10.5 bln/ml, then one should mix them in equal ratios. As a conservant one should introduce formalin, as an adjuvant - aluminum hydroxide at the following ratio of components, weight%: cell suspension of pure culture of Pseudomonas aeruginosa agent of ten sero-groups N18(01); N47(02); N37(03); N19(04); N2(06); N13(010), N70(011); N66(013); N29(018); N28(019) isolated out of local epizootic focus in nutritive medium at the titer being about 9.5-10.5 bln microbial cells/ml 84.6-89.5; formalin 0.4-0.5; aluminum hydroxide - the rest. The suggested vaccine is of high immunogenic activity.
EFFECT: higher efficiency.
5 ex, 1 tbl
Title | Year | Author | Number |
---|---|---|---|
STRAIN OF BACTERIA Pseudomonas aeruginosa FOR PRODUCTION OF VACCINE AGAINST PSEUDOMONOSIS OF PIGS | 2014 |
|
RU2553553C1 |
METHOD FOR MANUFACTURING VACCINE AGAINST PSEUDOMONOSIS IN SWINE | 2006 |
|
RU2309767C1 |
METHOD FOR MANUFACTURING OF POLYVALENT SERUM AGAINST PSEVDOMENOSIS OF AGRICULTURAL ANIMALS | 2008 |
|
RU2376034C1 |
Pseudomonas aeruginosa BACTERIUM STRAIN | 2014 |
|
RU2553306C1 |
STRAIN OF BACTERIA Pseudomonas aeruginosa FOR PRODUCTION OF VACCINE AGAINST PSEUDOMONOSIS OF PIGS | 2014 |
|
RU2553558C1 |
VACCINE ASSOCIATED WITH ESCHERICHIOSIS, STREPTOCOCCUS AND PSEUDOMONOSIS OF CATTLE | 2018 |
|
RU2695137C1 |
ASSOCIATED PSEUDOMONOSIS AND RABBIT VIRAL HAEMORRHAGIC DISEASE VACCINE | 2013 |
|
RU2531054C1 |
ASSOCIATED VACCINE AGAINST STREPTOCCOCOSIS, PSEUDOMONOSIS AND ENTEROCOCCUS INFECTION IN NUTRIA | 2009 |
|
RU2406531C1 |
METHOD FOR PRODUCING VACCINE ASSOCIATED WITH COLIBACILLOSIS, STREPTOCOCCUS AND PSEUDOMONOSIS OF BOVINE ANIMALS | 2018 |
|
RU2707289C1 |
VACCINE AGAINST PSEUDOMONOSIS OF NUTRIAS | 2008 |
|
RU2388488C1 |
Authors
Dates
2007-10-20—Published
2006-03-20—Filed