CGRP RECEPTOR ANTAGONISTS Russian patent published in 2007 - IPC C07D471/04 A61K31/4188 

Abstract RU 2308458 C2

FIELD: organic chemistry, pharmaceuticals.

SUBSTANCE: invention relates to compounds of formula I , wherein substituents meanings are as defined in specification, and pharmaceutically acceptable salts or individual diastereomers thereof. Claimed compounds are useful as CGRP receptors antagonists in treatment or prophylaxis of headache, migraine, etc. Also disclosed are pharmaceutical compositions containing such compounds and uses thereof in treatment or prophylaxis of abovementioned diseases mediated by CGRP.

EFFECT: new CGRP receptor antagonists.

5 cl, 6 tbl, 40 ex

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RU 2 308 458 C2

Authors

Bergi Kristofer S.

Dehn Chzhehnu Tsz

Ngujen Dim N.

Pehuan Dehniel V.

Sho Ehntoni U.

Uill'Jams Tereza M.

Dates

2007-10-20Published

2004-04-09Filed