SOLID MEDICINAL FORMULATION POSSESSING HISTAMINE-LIKE EFFECT AND METHOD FOR ITS PREPARING Russian patent published in 2007 - IPC A61K9/20 A61K9/48 A61K31/4402 A61P1/08 A61P27/16 

Abstract RU 2308941 C1

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to a solid medicinal formulation of agent used in prophylaxis and elimination vertigo and a method for its preparing. Agent comprises betahistine as active pharmaceutical component and special additives in the following ratio of components, wt.-%: betahistine hydrochloride, 4-16; microcrystalline cellulose, 25-70; acid stabilizing agent, 1-3; aerosil, 1-10; disintegrating substance, 1.2-5, and lactose, the balance. Invention provides good decomposition capacity and strength of tablet, simplifying preparing the medicinal formulation.

EFFECT: valuable pharmaceutical properties of formulation, improved preparing method.

8 cl, 2 tbl, 1 dwg, 8 ex

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RU 2 308 941 C1

Authors

Kuchugurin Vladimir Aleksandrovich

Barilenko Irina Ivanovna

Lazareva Ol'Ga Alekseevna

Karavanin Jurij Vjacheslavovich

Dates

2007-10-27Published

2006-05-10Filed