FIELD: medicine.
SUBSTANCE: tablet contains hydroxychloroquine sulphate and target additives in the following mixture ratio, wt %: a core: hydroxychloroquine sulphate - 36.24-46.24, calcium hydrogenphosphate dihydrate - 15.59-25.59, hypromellose - 3.0-10.0, croscarmellose sodium - 1.0-7.0, aerosil - 0.5-3.0, stearic acid and/or its salts - 0.5-1.0, Prosolv - the rest; a coating: hypromellose - 0.5-2.5, titanium dioxide - 0.15-0.80, macrogol - 0.05-0.50. Hydroxychloroquine tablets are produced by direct compression.
EFFECT: tablet is characterised by good disintegration and durability, and dissolves quickly; the production of the dosage form is simplified.
10 cl, 3 tbl
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