FIELD: medicine, cardiology.
SUBSTANCE: it is necessary to carry out medullary aspiration out of iliac crest to isolate autologous mononuclear medullary cells due to gradient centrifuging. They should be delivered into area of post-infarction myocardial necrosis due to introducing into coronary artery. Moreover, cellular suspension should be infiltrated into area of myocardial necrosis without preliminary cultivation at the quantity of about 70-110 mln. cells. For this purpose one should introduce a microcatheter into coronary artery so that arterial diameter and that of a microcatheter should coincide and it is necessary to supply the cells through it under the pressure of 2 atm. The innovation suggested enables to increase the quantity of mononuclear cells deposited in myocardium and decrease balloon's damaging impact upon the wall of coronary artery during introducing cellular suspension.
EFFECT: higher efficiency of therapy.
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Authors
Dates
2007-10-27—Published
2005-12-08—Filed