PYRIDINESULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITION BASED ON THE SAME AND USES THEREOF Russian patent published in 2007 - IPC C07D213/75 A61K31/44 A61P29/00 

Abstract RU 2309148 C2

FIELD: organic chemistry, pharmaceuticals.

SUBSTANCE: invention relates to new pyridinesulfonamide derivatives of general formula I , wherein A is nitrogen or -N=O group; X is oxygen, sulfur, or -NR3 (R3 is hydrogen, C1-C12-alkyl or C3-C8-cycloalkyl; R1 is mono- or polyhalogenated C1-C12-alkyl or mono- or polyhalogenated C3-C8-cycloalkyl; R2 is C3-C8-cycloalkyl or aryl group optionally substituted with one or more substituents as its defined in specification, and pharmaceutically acceptable salts thereof with pharmaceutically acceptable acids or bases; as well as pharmaceutical composition based on the same and uses thereof as therapeutically active substance in treatment of inflammation disorders.

EFFECT: new pyridinesulfonamide derivatives.

10 cl, 3 tbl, 19 ex

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RU 2 309 148 C2

Authors

Delarzh Zhak

Pirott Bernar

Don'E Zhan-Mishel'

De Leval' Ksav'E

Zhjulemon Fab'En

Dates

2007-10-27Published

2002-09-19Filed