HYDROQUINONE DERIVATIVES AS FREE OR SALT, METHODS OF THEIR SYNTHESIS, PIPERIDINE DERIVATIVES AND METHODS OF THEIR SYNTHESIS Russian patent published in 1997 - IPC

FIELD: organic chemistry. SUBSTANCE: products: derivatives of hydroquinone of the formula (I) where: R₄ - lower alkyl and R₁ - OH, halogen, -P(O)-(R₅)(R₆) or P⁺(R₇)(R₈)R₉X^-; M - methylene; R₂ - H or group of the formula (II) ; R₃ - H, halogen or R₁ - OH or lower alkoxyl group; M - carbonyl; R₂ - H and R₃ - halogen; R₅ and R₆ - lower alkoxyl group; R₇, R₈ and R₉ - phenyl; X^- - anion of hydrogen halide acid; Y - group -C(O); R₁₀ - lower alkyl group. Reagent 1: compound of the formula (III) which is halogenated, reduced and subjected for interaction with compound of the formula (IV) . Products: derivatives of piperidine of the formula (V) where: X₅ - halogen or group X₇ - O where: X₇ - lower alkanesulfonyl-group or alkoxycarbonyl-group; X_6/ - lower alkoxy-group, alkenylhydroxy-group, benzylhydroxy-group. Synthesized compounds were used as semiproducts for synthesis of antidepressants used in medicine. EFFECT: improved method of synthesis. 26 cl