FIELD: organic chemistry, derivatives of amino acids, medicine, pharmacy.
SUBSTANCE: invention relates to novel derivatives of phenylalanine that inhibit cellular adhesion mediated by α4 integrin that are considered to be useful in treatment and prophylaxis of inflammatory diseases. Invention relates to compounds of the formula (I): 
or its pharmaceutically acceptable salt, or ester wherein R1 means bromine atom; R2 means halogen atom, (C1-C6)-alkyl or (C1-C6)-alkoxy-group. Also, invention relates to a method for synthesis of compound of the formula (I), a pharmaceutical composition, using compound of the formula (I), in manufacturing a medicinal agent and to intermediate compounds of formulae (II) 
, (III) 
or (IV) 
.
EFFECT: valuable medicinal properties of derivatives and pharmaceutical composition.
17 cl, 10 ex
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