FIELD: organic chemistry, hematology.
SUBSTANCE: invention proposes an agent decreasing blood coagulation representing 4-acetyl-3-hydroxy-1-(2-hydroxyethylaminoethyl)-5-phenyl-3-pyrrolin-2-one of the formula (1): 
Agent elicits direct anti-coagulant effect as it reliably increases the time coagulation value of citrate blood by 30.4%.
EFFECT: valuable medicinal property of agent.
1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 1,4,5,6-TETRAHYDRO-6-OXO-5-(2-PIPERAZINOETHYL)-4-PHENYL-3-(4-CHLOROPHENYL)PYRROLO[3.4-C]PYRAZOLE DIHYDROCHLORIDE ELICITING HYPOTENSIVE AND ANTI-COAGULANT ACTIVITY | 2006 |
|
RU2320661C2 |
| METHYL 4-HYDROXY-4-METHYL-6-PHENYL-2-CYANOACETYLHYDRAZONOCYCLOHEXANE-1-CARBOXYLATE EXHIBITING ANALGESIC ACTIVITY | 2010 |
|
RU2446150C2 |
| MALEIC ACID 3-METHYL-2-PYRIDYLAMIDE ELICITING DIRECT ANTICOAGULANT EFFECT | 2005 |
|
RU2294199C2 |
| 4-ACETYL-5-(4-BROMOMETHYL)-3-HYDROXY-1-(3-HYDROXYPROPYL)-3-PYRROLIN-2-ONE, EXHIBITING NOOTROPIC ACTIVITY | 2008 |
|
RU2421446C2 |
| 2-(4'CHLOROPHENOXY)-N,N-DIETHYLETHANAMINE HYDROCHLORIDE MEDIUM WITH DIRECT ANTICOAGULATION EFFECT | 2007 |
|
RU2348610C2 |
| METHYL 6-ACETYL-7-(2,5-DIMETOXYPHENYL)-4,7-DIHYDROTETRASOLO[1,5-a]PYRIMIDINE-5-CARBOXYLATE, DEMONSTRATING ANTI-FEVER ACTIVITY | 2009 |
|
RU2413730C1 |
| THIAZOLINE AMMONIUM 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOATE, HAVING ANTICOAGULATION ACTIVITY | 2009 |
|
RU2461550C2 |
| 4,6-DIMETHYL-1H-2-OXONICOTINIC ACID 3-HYDROXYPROPYLAMIDE ELICITING ANTICOAGULANT, ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | 2006 |
|
RU2315040C1 |
| 2,2-DIMETHYL-4-(4,6-DIMETHYL-2-PYRIDON-3-YL)-1,2-DIHYDROBENZO[f]ISOQUINOLINE HYDROCHLORIDE ELECTING DIRECT ANTICOAGULANT EFFECT | 2006 |
|
RU2320654C1 |
| 1-(3,4-DIETHOXYPHENYL)-2,3,5,6-TETRAHYDRO-(3,4-DIETHOXYBENZO) [g]QUINOXALINO[2,3-b]INDOLIZINE HYDROCHLORIDE OF DIRECT ANTICOAGULATION EFFECT | 2006 |
|
RU2330850C1 |
