FIELD: organic chemistry, medicine, cardiology.
SUBSTANCE: invention proposes using derivatives of fumaric acid chosen from group consisting of dialkylfumarates, monoalkylhydrofumarates, fumaric acid monoalkyl ester salts, fumaric acid monoamides, fumaric acid diamides, monoalkyl-monoamidofumarates, carbocyclic isomers of these compounds and their mixture for preparing a pharmaceutical preparation used in treatment of asthma and chronic pulmonary obstructive diseases, in particular, asthma caused by allergy, infections, analgesic drugs, labor conditions or physical strength, asthma mixed forms or asthma cardiale. Dimethylfumarate decreased enhanced proliferation of bronchi smooth muscle cells.
EFFECT: valuable medicinal properties of compounds.
12 cl, 4 dwg, 7 ex
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