USING FUMARIC ACID DERIVATIVES FOR TREATING CARDIAC FAILURE, MYOCARDIAL INFARCTION AND ANGINA Russian patent published in 2012 - IPC A61K31/194 A61K31/231 A61P9/04 

Abstract RU 2459621 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is presented is using fumaric acid derivatives specified in a group consisting of dialkylfumarates, monoalkylhydrofumarates, fumaric acid monoalkyl ester salts, fumaric acid monoamides, fumaric acid monoamide salts, fumaric acid diamides, monoalkyl monoamido fumarates, carbocyclic and oxacarbocyclic oligomers of these compounds or their mixtures for preparing a drug for treatment or prevention of cardiac failure, particularly left-ventricular failure, myocardial infarction and angina.

EFFECT: dimethylfumarate has appeared to reduce considerably an area of infarction caused by ischemia followed by reperfusion.

19 cl, 4 dwg, 7 ex

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RU 2 459 621 C2

Authors

Dzhoshi Radzhendra Kumar

Shtrebel' Khans-Peter

Tsaugg Kristian

Tamm Mikhel'

Dates

2012-08-27Published

2007-10-15Filed