METHOD FOR PREPARING CRYSTALS, CRYSTALS AND PHARMACEUTICAL AGENT Russian patent published in 2008 - IPC C07J41/00 A61K31/56 A61K9/14 

Abstract RU 2314315 C2

FIELD: steroids, pharmacy.

SUBSTANCE: invention describes a method for preparing crystals showing the mean coarseness index in the required limits from 3 to 25 mcm and maximal size 100 mcm, not above. Method involves the crystallization process of supersaturated solution of compound representing 11β-benzaldoximestra-4,9-diene wherein it is subjected for wetted grinding by using the correspondence device designated for such wetted grinding to obtain suspension of primary grains. Also, invention crystals prepared by the proposed method and a pharmaceutical agent containing these crystals.

EFFECT: improved preparing method.

14 cl, 8 tbl, 4 dwg, 4 ex

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Authors

Grave Detlef

Gerekke Khagen

Khezel' Peter

Ajkhardt Annette

Glizing Zabine

Mjuller Uve

Dates

2008-01-10Published

2003-04-22Filed