FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new derivatives of 11β-benzaldoxime-estradiene of the general formula (I) 11β where values 
, Z are indicated in p. 1 of the invention claim, and their pharmaceutically acceptable salts, a method of their synthesis and pharmaceutical compositions containing these compounds. Described compounds show the strong antigestagenic property at more insignificant glucocorticoid activity. EFFECT: improved method of synthesis, enhanced antigestagenic activity. 16 cl, 15 ex
| Title |
Year |
Author |
Number |
| DERIVATIVES OF 11β--BENZALDOXIME-ESTRA-4,9-DIENE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION |
1994 |
- Gerd Shubert
- Gjunter Kaufmann
- Lotar Zobek
- Mikhael' Oettel'
- Val'Ter Ehl'Ger
- Anatoli Kurishko
|
RU2130944C1 |
| SULFAMATE DERIVATIVES, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS |
1996 |
- Zigfrid Shvarts
- Val'Ter Ehl'Ger
- Gudrun Reddersen
- Birgitt Shnajder
- Ina Time
- Margit Rikhter
|
RU2159774C2 |
| DERIVATIVES OF ESTRA-1,3,5(10)-TRIENE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1995 |
- Zigfrid Shvarts
- Val'Ter Ehl'Ger
- Khans-Ioakhim Ziman
- Gudrun Reddersen
- Birgitt Shnajder
|
RU2139885C1 |
| HORMONAL OR ANTI-HORMONAL STEROID COMPOUNDS, METHODS FOR THERAPEUTIC EFFECT, METHOD FOR PREPARING COMPOUNDS |
1999 |
- Kuk K. Ehdgar
- Kepler Dzhon A.
- Bartli Gari S.
- Shetti Rupa S.
|
RU2238943C2 |
| PROGESTERONE ANTAGONISTS |
2012 |
- Nickisch Klaus
- Narkunan Kesavaram
- Debnath Baishakhi
- Santhamma Bindu
|
RU2608521C2 |
| DERIVATIVES OF 11,21-BISPHENYL-19-NORPREGNANE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING |
1995 |
- Gebkhar Ronal'D
- Van Der Vort Khendrikus Adrianus Antonius
|
RU2152952C2 |
| DERIVATIVE OF 11-(PHENYL-SUBSTITUTED)-ESTRA-4,9-DIENE, METHOD OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1996 |
|
RU2135514C1 |
| METHOD OF SYNTHESIS OF 17β-HYDROXY-11β-[4-(DIMETHYLAMINO)- -PHENYL]-17α-(PROP-1-INYL)-ESTRA-4,9-DIENE-ONE |
2000 |
- Rusinov M.E.
- Chertorizhskij E.A.
|
RU2165938C1 |
| PROGESTERONE RECEPTOR MODULATORS |
2005 |
- Khamersma Jokhannes Antonius Marija
- Revinkel Jokhannes Bernardus Marija
|
RU2381232C2 |
| DERIVATIVES OF 16-HYDROXY-11-(SUBSTITUTED PHENYL)-ESTRA-4,9-DIENE, COMPOUND, PHARMACEUTICAL COMPOSITION |
1998 |
- Grun Marinus Bernard
- Gebkhard Ronal'D
|
RU2187510C2 |
