FIELD: medicine, pharmacy.
SUBSTANCE: invention describes a pharmaceutical composition for oral using as a tablet designated for treatment of bone diseases and some disturbances of calcium metabolism. A table core comprises bisphosphonates or their physiologically safe salts as an active substance. Preferably, the active substance is ibandronic acid. Preferably, a table core comprises 100 mg or 150 mg of bisphosphonates or equivalent amount of their physiologically safe salts. Also, invention describes a method for preparing the composition by addition of a raising agent at granulation step simultaneously with bisphophonate and part of raising agent. Invention provides enhanced stability of tablets in their storage by such parameters as temperature and humidity.
EFFECT: improved and valuable pharmaceutical properties of composition.
16 cl, 2 ex
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