MEDICINAL FORMS ON BASIS OF BIPHOSPHONATES Russian patent published in 2009 - IPC A61K31/66 A61K9/22 A61K9/52 A61K47/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention concerns medicine area, namely to peroral medicinal forms on a basis of biphosphonates, containing safe and effective quantity of the pharmaceutical composition containing biphosphonate, chelated agent and an agent for effective delivery of a pharmaceutical composition in the bottom gastroenteric tract of a mammal, and also pharmaceutically active biphosphonate absorption together with nutrition or drinks or without them. The present invention essentially reduces interaction between biphosphonates and nutrition or a drink, which (interaction) leads to that active biphosphonate component is not accessible to absorption. The final peroral medicinal form can be accepted both with food, and without it. Further, the present invention influences delivery biphosphonate and chelated agent in a bottom of GI tract, essentially reducing irritation of top of the GI tract, bound with biphosphonate therapy.

EFFECT: maintenance of fuller observance with the patient of a regimen biphosphonate therapy.

23 cl, 20 ex