FIELD: agents for controlling of mouse-like rodents.
SUBSTANCE: invention relates to purification of 1,3-indandione 2-acyl-derivatives which are blood anticoagulants of nondirect action useful in controlling of mouse-like rodents. Claimed method includes precipitation of 1,3-indandione 2-acyl-derivatives followed by decomposition thereof with strong acid, wherein 1,3-indandione 2-acyl-derivatives are precipitated with copper(II) salts in copper salt/1,3-indandione 2-acyl-derivative of (1.1-1.9):1, ant temperature of 40-60°C in medium of solvating organic solvent. Precipitate of copper-containing salt of 1,3-indandione 2-acyl-derivative is treated with potassium hydroxide, then with sulfur acid followed by extraction with chloroform.
EFFECT: simplified process; increased purification level.
1 tbl, 16 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREPARING INDANEDIONES-1,3 | 2002 |
|
RU2224739C2 |
| METHOD OF PREPARING 2 [ALPHA-PHENYL-ALPHA-(ETHYL) PHENYLACETYL] INDANDIONE-1,3 | 1996 |
|
RU2116291C1 |
| REDENTICIDE CONCENTRATE | 0 |
|
SU1584736A3 |
| PROCESS FOR PREPARING DERIVATIVES OF 1-ACYL-2-CYANOAZIRIDINES OR THEIR SALTS | 0 |
|
SU1077565A3 |
| 0 |
|
SU180178A1 | |
| CRYSTALLINE MODIFICATION 2-[(4-CHLOROPHENYL) PHENYLACETYL]-1H-INDENE-1,3(2H)-DIONE (CHLOROFACINONE) AND A METHOD FOR ITS PREPARATION | 2020 |
|
RU2748131C1 |
| METHOD OF OBTAINING 3-IMINOMETHYLRIFAMYCIN DERIVATIVES | 0 |
|
SU613725A3 |
| METHOD OF OBTAINING 3-(4-SUBSTITUTED PHENYL)-5-ACYLAMIDOMETHYLOXAZOLIDINONS-2 | 0 |
|
SU1528317A3 |
| METHOD OF PREPARING OXYGEN-CONTAINING HETEROGENEOUS RING COMPOUNDS OR THEIR METAL SALTS | 0 |
|
SU577999A3 |
| PRODRUGS OF 3-ACYL-2-HYDROXYINDOLE-1-CARBOXAMIDES, PHARMACEUTICAL COMPOSITION | 1993 |
|
RU2124514C1 |
