METHOD FOR MODELING CHOLESTATIC HEPATITIS Russian patent published in 2008 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: method involves evoking peripheral segment irritation of sympathetic trunk at the level of V-VII cervical vertebrae with rectangular pulses having amplitude of 4-12.5 V, frequency of 5-7 Hz, pulse duration of 1-5 mcs. Vagus nerve irritation is added in 10-13 s on this background at the level of V-VII cervical vertebrae with rectangular pulses having amplitude of 1.5-7.5 V, frequency of 5-7 Hz, pulse duration of 1-5 mcs during 1.5-2 min. The vagus nerve stimulation is stopped in 1.5-2 min and sympathetic is also stopped in 5-10 s. Combined nerve irritation is carried out 4-6 times per 1 h during 8-12 h.

EFFECT: high accuracy and reproducibility of modeling results.