FIELD: organic chemistry, medicine, oncology.
SUBSTANCE: invention describes N-substituted indolyl-3-glyoxylamides of the formula (I): 
wherein R1, R3-R6 mean hydrogen atom; R2 means alkylaryl substituted with chlorine atom; R7 is chosen from group comprising the following radicals: sulfone of the formula -SO2-X1, -C(O)-X2, -C(O)O-X3 wherein X and Y means oxygen atom (O); HET means unsaturated (C6-C10)-heterocycle comprising heteroatom representing nitrogen atom. Also, invention relates to a method for synthesis of these compounds and their using as an antiproliferative agent and firstly in treatment of tumors.
EFFECT: valuable medicinal properties of compounds.
9 cl, 7 tbl, 8 ex
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