METHOD OF OBTAINING TOTAL AMOUNT OF PHENOL ACID FROM MULTI-ROOTED SAGE (SALVIA) AND USE THEREOF Russian patent published in 2008 - IPC C07C67/56 C07C67/58 C07C69/675 C07D307/84 A61K36/185 A61K31/185 A61K36/53 A61K31/19 A61K31/192 A61K31/34 A61P9/10 A61P25/28 

FIELD: biologically active substances.

SUBSTANCE: invention relates to improved method of obtaining total amount of phenol acid including following steps: (a) multi-rooted sage is extracted with water and filtered; (b) filtrate is placed in polyamide column and washed with water to neutral reaction, wash water is removed, and polyamide column is eluted with weak aqueous alkali solution, and obtained fractions are connected; (c) alkali fractions obtained in step (b) are acidified and placed in absorption column with macroporous resin, column is washed to neutral state, wash water is removed, column is eluted with aqueous or anhydrous lower alcohol, eluent is collected, evaporated at reduced pressure to remove alcohol, and dried. Yield of final product exceeds 4% based on amount of crude drug and content of total amount of phenol acid exceeds 80%. Thus obtained total amount of phenol acid can be used as drug for prevention and treatment of brain vessel diseases.

EFFECT: enlarged resource of vegetable material for preparation of vascular drugs.

15 cl, 7 ex