METHOD FOR PRODUCING POLARIZED LYMPHOCYTES FOR MODELING Th2-INDUCED EDEMA Russian patent published in 2008 - IPC A61K35/28 A61K38/38 

Abstract RU 2318525 C1

FIELD: medicine.

SUBSTANCE: method involves carrying out conventional mice hyperimmunization of BAlb/c for producing polarized lymphocytes with three-fold subcutaneous ovalbumin introduction at a dose of 100 mcg/mouse and aluminum hydroxide adjuvant introduction at a dose of 5 mg/mouse making 14 days long pause between injections. Spleens are taken and lymphocytes are separated 7 days later after the last injection.

EFFECT: simplified method for obtaining polarized TH-2 lymphocytes in the amount for modeling immune response of TH-2 type.

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Authors

Gol'Dberg Evgenij Danilovich

Dygaj Aleksandr Mikhajlovich

Agafonov Vladimir Ivanovich

Bel'Skij Jurij Pavlovich

Bel'Skaja Natal'Ja Vital'Evna

Danilets Marina Grigor'Evna

Trofimova Evgenija Sergeevna

Dates

2008-03-10Published

2006-06-29Filed